Polyamines: mysterious modulators of cellular functions.

By K. Igarashi, K. Kashiwagi. Biochemical and Biophysical Research Communications - BBRC, 2000

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Polyamines: essential factors for growth and survival (2008, background): “Polyamines are considered to be essential for life, as inhibition of polyamine biosynthesis blocks cell growth (Cohen 1998; Igarashi and Kashiwagi 2000; Thomas and Thomas 2001; Hanfrey et al. 2001).”
Polyamine accumulation in transgenic eggplant enhances tolerance to multiple abiotic stresses and fungal resistance (2007, background): “2006), they also play an important role in the regulation of various cellular and molecular processes including growth and development, membrane integrity, macromolecular synthesis and function (Igarashi and Kashiwagi 2000; Thomas and Thomas 2001; Kumar et al. 2006).”
Polyamines: molecules with regulatory functions in plant abiotic stress tolerance (2010, background): “However, it was later conWrmed that in addition to stabilizing macromolecular structures, polyamines act as regulatory molecules in many fundamental cellular processes (Igarashi and Kashiwagi 2000; Seiler and Raul 2005; Alcázar et al. 2006b; Kusano et al. 2008).”
Important roles for the arginine family of amino acids in swine nutrition and production (2007, neutral): “Likewise, polyamines regulate DNA and protein synthesis, and, therefore, cell proliferation and differentiation (Igarashi and Kashiwagi, 2000).”