Representation of the elderly, women, and minorities in heart failure clinical trials.
By A. Heiat, C. Gross, Harlan M. Krumholz. Archives of Internal Medicine, 2002
725 citations recorded by the source corpus.
Subfields: Cardiology and Cardiovascular Medicine
View Paper: https://www.semanticscholar.org/paper/bb43a6e40fa8c59b91963c1d6c7e45c4cde9ea9c
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Citations in the corpus
- Noncardiac comorbidity increases preventable hospitalizations and mortality among Medicare beneficiaries with chronic heart failure. (2003, background): “treatment trials typically exclude elderly patients and those with one or more significant comorbidities (38,39).”
- Systolic blood pressure at admission, clinical characteristics, and outcomes in patients hospitalized with acute heart failure. (2006, neutral): “Bed size 0-99 31 (12) 9 (10) 100-249 58 (22) 21 (23) 250-499 103 (40) 40 (44) 500-749 38 (15) 13 (14) 750 13 (5) 4 (4) Unknown 16 (6) 4 (4) Academic 118 (48) 48 (55) Transplant program 34 (14) 9 (10) Interventional (CABG surgery/PCI) 163 (67) 62 (70)”
- Reaching the hard-to-reach: a systematic review of strategies for improving health and medical research with socially disadvantaged groups (2014, background): “In most Western developed countries white, middle class, highly educated males tend to be overrepresented in health and medical research and people from socially disadvantaged groups under-represented [1,2].”
- Are Racial and Ethnic Minorities Less Willing to Participate in Health Research? (2005, background): “The claim that racial and ethnic minority groups in the US are less willing to participate in health research seems to be validated by data showing that minority groups are underrepresented in at least some health research studies [20–25].”
- External validity of randomised controlled trials in asthma: to whom do the results of the trials apply? (2006, neutral): “This last requirement is not always met and it is recognized that older adults, women and ethnic minorities may be underrepresented in RCTs.(2-5) Design considerations often lead to RCTs that are performed in highly selected patient populations such as those with the most typical features of a disea”