Deformation of DNA molecules by hydrodynamic focusing

By P. Wong, Yi-Kuen Lee, Chih-Ming Ho. Journal of Fluid Mechanics, 2003

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The hydrodynamic focusing effect inside rectangular microchannels (2006, background): “The flow focusing technique provides a particularly effective means of controlling the passage of chemical reagents or bio-samples through the microchannels of microfluidic devices and has been successfully demonstrated in a wide variety of applications, including flow cytometers for cell/particle c”
Microfluidics: Fluid physics at the nanoliter scale (2005, background): “26 Perkins et al., 1997; Smith and Chu, 1998; Schroeder et al., 2003 or flow focusing Wong et al., 2003 , and were complemented by Brownian dynamics studies Larson et al., 1999; Maroja et al., 2001; Hur et al., 2002 .”
Three-dimensional hydrodynamic focusing in two-layer polydimethylsiloxane (PDMS) microchannels (2007, background): “Recently, two-dimensional hydrodynamic focusing and electrokinetic focusing have been successfully demonstrated in a wide variety of microfluidic applications, including in micro-flow cytometers for cell/particle counting and sorting [8–11], DNA stretching [12], micro flow switches [7, 13], rapid di”