Different plant hormones regulate similar processes through largely nonoverlapping transcriptional responses.

By Jennifer L. Nemhauser, Fangxin Hong, Joanne Chory. Cell, 2006

915 citations recorded by the source corpus.

Small-molecule hormones govern every aspect of the biology of plants. Many processes, such as growth, are regulated in similar ways by multiple hormones, and recent studies have revealed extensive crosstalk among different hormonal signaling pathways. These results have led to the proposal that a common set of signaling components may integrate inputs from multiple hormones to regulate growth. In this study, we tested this proposal by asking whether different hormones converge on a common set of transcriptional targets in Arabidopsis seedlings. Using publicly available microarray data, we analyzed the transcriptional effects of seven hormones, including abscisic acid, gibberellin, auxin, ethylene, cytokinin, brassinosteroid, and jasmonate. A high-sensitivity analysis revealed a surprisingly low number of common target genes. Instead, different hormones appear to regulate distinct members of protein families. We conclude that there is not a core transcriptional growth-regulatory module in young Arabidopsis seedlings.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/bb02f0c9b3faaaac1c6fdd6ed93315083071f9f2

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

In Plant Science

Citations in the corpus

Auxin Control in the Formation of Adventitious Roots (2011, neutral): “Over the last years, a multitude of models have been proposed to show how plant hormones interact to control plant development (Jaillais and Chory, 2010; Nemhauser et al. , 2006; Santner and Estelle, 2009).”
Plant hormones in salt stress tolerance (2015, background): “Plant hormone crosstalk can occur at the level of regulating hormone biosynthesis, signal transduction or common target gene expression (Nemhauser et al. 2006).”
The Regulation of Brassinosteroid Biosynthesis in Arabidopsis (2013, background): “…elongation was inhibited in a BR biosynthetic mutant background, implying that temperature-dependent hypocotyl elongation may require increased levels of BR biosynthesis and that BR is necessary for hypocotyl elongation in high temperatures (Nemhauser et al., 2006; Maharjan and Choe, 2011).”
Participation of abscisic acid and gibberellins produced by endophytic Azospirillum in the alleviation of drought effects in maize (2009, background): “In Arabidopsis seedlings, ABA antagonizes growth promotion by GAs (Nemhauser et al. 2006), and plants carrying mutations in the DELLA genes (that encode negative regulators of GAs) exhibit altered response to exogenous ABA (Achard et al.”
Global transcriptome analysis reveals circadian regulation of key pathways in plant growth and development (2008, background): “This is reminiscent of the limited overlap between hormone-responsive genes in general; multiple hormones may regulate the expression of a family of genes with similar functions, but each individual gene is seldom controlled by more than one or two hormones [57].”
Abscisic Acid and Abiotic Stress Tolerance in Crop Plants (2016, background): “Many studies reported that almost 10% of the Arabidopsis genes are regulated by ABA (Hoth et al., 2002; Nemhauser et al., 2006; Yang et al., 2008).”
Chapter Two – How the Plant Growth-Promoting Bacterium Azospirillum Promotes Plant Growth—A Critical Assessment (2010, neutral): “In this stress mitigation process, ABA–GAs were investigated with Azospirillum inocula tion even though ABA and GAs have antagonistic roles in many processes of plant growth (Achard et al., 2006; Nemhauser et al., 2006).”
The role of ABA and MAPK signaling pathways in plant abiotic stress responses. (2014, background): “In Arabidopsis, about 10% of all genes are regulated by ABA (Hoth et al., 2002; Nemhauser et al., 2006; Seki et al., 2002).”
The AtGenExpress hormone and chemical treatment data set: experimental design, data evaluation, model data analysis and data access. (2008, methodology): “Nemhauser et al. (2006) used our data to analyze hormone networks from the point of view of hormone metabolism.”
The relationship of drought-related gene expression in Arabidopsis thaliana to hormonal and environmental factors (2008, neutral): “Similarly, among drought-downregulated genes there was enrichment of terms related to structural molecule activity, ribosome, biosynthesis, metabolism, water channel activity, photosynthesis, and porphyrin metabolism.”