Tetrazolium dyes as tools in cell biology: new insights into their cellular reduction.

By M. Berridge, P. Herst, A. Tan. Biotechnology Annual Review, 2005

2,077 citations recorded by the source corpus.

Subfields: Biophysics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/bae5bb26f8a5e7950f28a197a52bb53bd47e8dc8

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In Molecular Biology

1. Tyron Turnbull
2. M. Ghasemi
3. S. Sebastian
4. I. Kempson

Citations in the corpus

• MTT assay for cell viability: Intracellular localization of the formazan product is in lipid droplets. (2012, methodology): “, MTT, NBT) ppears to be a relevant factor involved in their cellular uptake ia the plasma membrane potential (Berridge et al., 2005).”
• The MTT Assay: Utility, Limitations, Pitfalls, and Interpretation in Bulk and Single-Cell Analysis (2021, background): “Reduction of MTT results in disruption of the core tetrazole ring and the formation of a violet-blue water-insoluble molecule called formazan [1].”