Acetylcholinesterase knockouts establish central cholinergic pathways and can use butyrylcholinesterase to hydrolyze acetylcholine.

By Marsel Mesulam, A. Guillozet, Pamela L. Shaw, A. Levey, E. Duysen, O. Lockridge. Neuroscience, 2002

613 citations recorded by the source corpus.

Subfields: Computational Theory and Mathematics, Molecular Biology, Pharmacology

View Paper: https://www.semanticscholar.org/paper/bac9072f4c03720746de54d7c0d25c39610d793d

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In Pharmacology

1. Francesco Amenta

Citations in the corpus

• Efficacy of acetylcholinesterase inhibitors in Alzheimer's disease. (2020, background): “In the cerebral cortex, AChE is present in the nerve synaptic junctions, whereas BuChE is located in the glial cells and modulates cholinergic neurotransmission (Mesulam et al., 2002; Wright et al., 1993; Mesulam and Geula, 1991).”
• Neurobiology of butyrylcholinesterase (2003, neutral): “, is a co-regulator of cholinergic neurotransmissio”