Disrupting tumour blood vessels

By G. Tozer, C. Kanthou, B. Baguley. Nature Reviews. Cancer, 2005

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Microtubule-binding agents: a dynamic field of cancer therapeutics (2010, background): “The two approaches to inhibiting vascular function are to inhibit angiogenesis — the formation of new blood vessels — using anti-angiogenic agents and to destroy the integrity of existing tumour vasculature using vascular-disrupting agent”
Photodynamic therapy of cancer. Basic principles and applications (2008, background): “These hypoxic vascular effects are associated with the inhibition or delay of tumour growth [1, 4, 36, 37].”