Myocardial Structure and Function Differ in Systolic and Diastolic Heart Failure

By L. van Heerebeek, A. Borbély, H. Niessen, J. Bronzwaer, J. van der Velden, G. Stienen, W. Linke, G. Laarman, W. Paulus. Circulation, 2006

659 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Coronary Microvascular Rarefaction and Myocardial Fibrosis in Heart Failure With Preserved Ejection Fraction (2015, background): “HFpEF patients with EF 50% at diagnosis tended to have less severe CAD at autopsy (CAD total score 12 (7-14)) than HFpEF patients with EF 40-49% at HF diagnosis (12.”
A novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation. (2013, positive): “A comparative analysis of endomyocardial biopsy samples from HFPEF and HFREF (3,27) indeed showed the presence of replacement ﬁ brosis in HFREF but not in HFPEF.”
Sense and stretchability: the role of titin and titin-associated proteins in myocardial stress-sensing and mechanical dysfunction. (2007, background): “The effect may be interesting from a therapeutic point of view, because raising myocardial PKA activity by beta-adrenoceptor stimulation could improve the left-ventricular diastolic function in patients with diastolic HF [ 89 ].”