Negative functional MRI response correlates with decreases in neuronal activity in monkey visual area V1

By Amir Shmuel, Mark-Aurel Augath, A. Oeltermann, Nikos K. Logothetis. Nature Neuroscience, 2006

911 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/ba1247171620cc84fa5fcfca30e5fb9966391dab

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Citations in the corpus

The effects of electrical microstimulation on cortical signal propagation (2010, background): “Sustained cortical NBRs have been reported during sensory stimulation and reflect regional decreases in neuronal activity below spontaneous activit”
Neuroimaging and Inferential Distance (2008, methodology): “Our confidence in our ability to relate changes in the fMRI signal to neural activity is dependent upon empirical generalization and corroboration by other methods that more directly measure metabolic demands and blood flow [2, 17, 23].”
Phase patterns of neuronal responses reliably discriminate speech in human auditory cortex. (2007, background): “…auditory information processing at such disparate scales is linked—what mechanisms can encode responses at the single-neuron level and couple these to responses in cortical cell assemblies—remains one of the most challenging questions in neuroscience (Logothetis et al., 2001; Shmuel et al., 2006).”
Human brain mapping: hemodynamic response and electrophysiology. (2008, background): “So far the majority of studies using fMRI focused upon the positive BOLD activity (signal increase by stimulus or task as compared with control condition), but recently the negative BOLD activity (lower level of BOLD response than the control) has drawn attention (Stefanovic et al., 2004; Lauritzen,”
Trial-by-trial coupling between EEG and BOLD identifies networks related to alpha and theta EEG power increases during working memory maintenance (2009, background): “…et al. (2001) who found that the BOLD signal showed a strong positive correlation with gamma band activity observed in local fields potentials (LFP) in monkeys, and Shmuel et al. (2006), who reported that negative BOLD responses go together with a decrease in gamma band activity in the LFP.”
Coupling between neuronal firing rate, gamma LFP, and BOLD fMRI is related to interneuronal correlations. (2007, methodology): “Such a linear relationship was also demonstrated empirically with simultaneous recordings in the anesthetized rat [17, 18] and for negative BOLD responses in anesthetized monkeys [8].”
A default mode of brain function: A brief history of an evolving idea (2007, background): “11 It should also be noted that the work of Shmuel and colleagues (Shmuel et al., 2006) provided us with the first direct evidence that activity decreases seen with fMRI represented actual reductions in neuronal activity. may be applied equally well to both PET and fMRI imaging techniques.”
Flexibility and Stability in Sensory Processing Revealed Using Visual-to-Auditory Sensory Substitution (2014, background): “tive BOLD signal are still being studied (Shmuel et al. 2006; Schridde et al. 2008; Azulay et al. 2009), the above studies and others show that these deactivations have functional implications (Kastrup et al.”
Neuronal correlates of spontaneous fluctuations in fMRI signals in monkey visual cortex: Implications for functional connectivity at rest (2008, methodology): “Data were obtained in nine sessions from seven healthy, anesthetized monkeys (macaca mulatta, 6-9 kg).”
Dynamic causal modelling: A critical review of the biophysical and statistical foundations (2011, background): “So far, it neglects the potential influence of inhibitory activity on the hemodynamic response, which is a likely explanation for deactivations (Sotero and Trujillo, 2007; Shmuel et al. 2006).”
The brain's default mode network. (2015, neutral): “We (Drevets et al. 1995) and others (Amedi et al. 2005, Ghatan et al. 1998, Kawashima et al. 1995, Shmuel et al. 2006, Smith et al. 2000, Somers et al. 1999) had noted other more task-speciﬁc deactivations, consistent”
Less Is More: Expectation Sharpens Representations in the Primary Visual Cortex (2012, positive): “Additionally, a recent combined hemodynamic/neurophysiological study reported hemodynamic and metabolic downregulation following neuronal inhibition in the visual cortex of monkeys (Shmuel et al., 2006).”