Thyroid status, disability and cognitive function, and survival in old age.

By J. Gussekloo, E. V. van Exel, A. D. de Craen, A. Meinders, M. Frölich, R. Westendorp. Journal of the American Medical Association (JAMA), 2004

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Small differences in thyroid function may be important for body mass index and the occurrence of obesity in the population. (2005, background): “subjects with overt thyroid dysfunction were included (10).”
Global epidemiology of hyperthyroidism and hypothyroidism (2018, positive): “In iodine sufficient countries, the prevalence of hypothyroidism ranges from 1-2% 10,91 rising to 7% in individuals aged between 85-89 years 92 .”
The clinical significance of subclinical thyroid dysfunction. (2008, background): “Moreover, two other studies (92, 194) involved selected populations (atomic bomb survivors and 85-yr-old individuals), thereby limiting the generalizability of the findings.”
Guidelines for the Treatment of Hypothyroidism: Prepared by the American Thyroid Association Task Force on Thyroid Hormone Replacement (2014, positive): “There are observational data showing decreased mortality rates (258) and improved measures of well-being (259) in elderly persons with TSH levels that are above the traditional reference range (i.”
Hyperthyroidism and Other Causes of Thyrotoxicosis: Management Guidelines of the American Thyroid Association and American Association of Clinical Endocrinologists (2011, background): “One cross-sectional (266) and one longitudinal (267) study of older individuals showed no changes in cognitive function, whereas two others suggested an association between SH and dementia in older persons (268,269).”