Geometry and Structural Plasticity of Synaptic Connectivity

By Patrick R. Hof, Dmitri "Mitya" Chklovskii. 2002

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Citations in the corpus

Dendritic spines and distributed circuits. (2011, unknown): “Reproduced with permission from ‘‘Herederos de Santiago Ramón y Cajal.’’ from Cajal on: spines could help to connect with axons, by sampling a cylindrical volume around the dendrite, as a ‘‘virtual dendrite’’ (Ramón y Cajal, 1899; Stepanyants et al., 2002; Swindale, 1981; Ziv and Smith, 1996).”
Learning rules and persistence of dendritic spines (2010, background): “This has not been studied directly, but it is known that the number of possible synaptic connections between a dendrite and axon is several times greater than the number of existing connections (Stepanyants et al., 2002).”
Experience-dependent structural synaptic plasticity in the mammalian brain (2009, background): “Compared with synaptic strength changes alone, such structural spine plasticity would hugely increase the memory storage capacity of the brain, because a large number of synaptic connectivity patterns are attainable by spine or bouton growth, even without large-scale remodelling of dendritic and axo”
Massive restructuring of neuronal circuits during functional reorganization of adult visual cortex (2008, result): “This hypothesis fits well with a recent quantitative anatomical study, which found that the number of axons close to a dendrite in mouse neocortex is sufficiently high to allow for reorganization to occur by spine changes alone, without dendritic or axonal remodelin”
Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex (2002, background): “A separate model suggests changes in cortical connectivity at the level of individual synapses, without large-scale rearrangements of neuronal processe”
Activity-dependent structural plasticity. (2009, background): “How much impact spontaneous synaptic rewiring has on the function of neuronal networks depends on the filling fraction of the network (Stepanyants et al., 2002), which is a measure for the amount of potential synapses.”
Memory Capacities for Synaptic and Structural Plasticity (2010, background): “This idea assumes that the network structure can be adapted to the stored data and has close relations to theoretical considerations about structural plasticity (Stepanyants, Hof, & Chklovskii, 2002 ; Poirazi & Mel, 2001 ; Fusi, Drew, & Abbott, 2005 ).”
The Human Connectome: A Structural Description of the Human Brain (2005, background): “These changes include synaptic weights as well as structural remodeling of dendritic spines and presynaptic boutons [21], possibly switching synaptic connections between large numbers of potential synaptic sites [22,23].”