Tissue microarrays for rapid linking of molecular changes to clinical endpoints.
By J. Torhorst, C. Bucher, J. Kononen, Philippe Haas, M. Zuber, Ossi R. Köchli, F. Mross, H. Dieterich, H. Moch, M. Mihatsch and 2 more. American Journal of Pathology, 2001
617 citations recorded by the source corpus.
Subfields: Molecular Biology, Oncology, Radiology, Nuclear Medicine and Imaging
View Paper: https://www.semanticscholar.org/paper/b8f91df56cd32edf6798afc4a3f319a88997fc16
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In Molecular Biology
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In Oncology
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Citations in the corpus
- Identification of tumor epithelium and stroma in tissue microarrays using texture analysis (2012, background): “Tissue microarrays (TMAs) are the standard for high-throughput analysis of diagnostic, prognostic and predictive tissue biomarkers [1] and for rapid validation of molecular expression patterns in large-scale tissue materials [2].”
- Virtual Microscopy and Grid-enabled Decision Support for Large Scale Analysis of Imaged Pathology Specimens (2009, background): “These findings were reported for a range of disorders including breast cancer [5], [6], prostate cancer [7], and gastric cancer [8].”
- X-Tile (2004, result): “Because prior studies have shown that a single core adequately represents the staining pattern of an entire slide, all studies were done with a single sample of each tumor (7, 8).”
- Expression of luminal and basal cytokeratins in human breast carcinoma (2004, methodology): “Breast cancer tissue microarrays were prepared as described previously [17–19].”
- The novel marker, DOG1, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of KIT or PDGFRA mutation status. (2004, methodology): “6-mm cores from formalin-fixed, paraffin-embedded tumor assembled using a semiautomated tissue arrayer.(21) There was one core for each tumor, and all of the GISTs on this TMA were analyzed for mutations in exons 9, 11, 13, and 17 of the KIT gene using a combination of denaturing high pressure liqui”