Biochemistry and Genetics of Insect Resistance to Bacillus thuringiensis

By J. Ferré, J. Rie. 2002

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A review on biological interactions and management of the cotton bollworm, Helicoverpa armigera (Lepidoptera: Noctuidae) (2021, background): “…both Cry2Ab and Cry1Ac in the same plant) have been commercially used for a number of years to slow the development of Bt resistance in H. armigera (Ferré & Rie, 2002), with three stacked genes also now available commercially (e.g. Roundup Ready Flex and Bollgard 3®) (Cotton Australia, 2020;…”
Fitness cost, cross resistance and realized heritability of resistance to imidacloprid in Spodoptera litura (Lepidoptera: Noctuidae) (2012, background): “Managing resistance to insecticides depends on associated fitness costs such that the frequency of resistance alleles will decline when selection is reduced [79].”
Bacillus thuringiensis and its pesticidal crystal proteins (2020, neutral): “thuringiensis appears to be indigenous ([11]).”