A Rewritable, Random-Access DNA-Based Storage System
By S. M. Hossein, Tabatabaei Yazdi, Yongbo Yuan, Jian Ma, Huimin Zhao, Olgica Milenkovic. Scientific Reports, 2015
405 citations recorded by the source corpus.
We describe the first DNA-based storage architecture that enables random access to data blocks and rewriting of information stored at arbitrary locations within the blocks. The newly developed architecture overcomes drawbacks of existing read-only methods that require decoding the whole file in order to read one data fragment. Our system is based on new constrained coding techniques and accompanying DNA editing methods that ensure data reliability, specificity and sensitivity of access and at the same time provide exceptionally high data storage capacity. As a proof of concept, we encoded parts of the Wikipedia pages of six universities in the USA and selected and edited parts of the text written in DNA corresponding to three of these schools. The results suggest that DNA is a versatile media suitable for both ultrahigh density archival and rewritable storage applications.
Subfields: Biomedical Engineering, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/b8a0a9fd069348261ea4983f9182c90b5340fc95
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Biomedical Engineering
In Molecular Biology
Citations in the corpus
- Random access in large-scale DNA data storage (2018, neutral): “As expected, the ratio decreased with”
- Portable and Error-Free DNA-Based Data Storage (2016, background): “Selectivity is achieved by prohibiting the appearance of the address sequence anywhere in the encoded DNA blocks 3,14 .”