Three-Dimensional Cell Culture Systems and Their Applications in Drug Discovery and Cell-Based Biosensors

By R. Edmondson, Jessica Jenkins Broglie, Audrey F. Adcock, Liju Yang. Assay and drug development technologies, 2014

2,256 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/b776327dc8212170baef1e24100eaa4c60246ddb

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In Biomedical Engineering

1. Sigrid A. Langhans

In Molecular Biology

1. Sigrid A. Langhans

Citations in the corpus

• Modeling Physiological Events in 2D vs. 3D Cell Culture. (2017, background): “For instance, in aggregated spheroids, the highest levels of proliferation are at the surface, whereas the interior of the 3D cell bodies possesses the highest number of quiescent or necrotic cells (31).”
• Three-Dimensional in Vitro Cell Culture Models in Drug Discovery and Drug Repositioning (2018, background): “Application of 3D cell culture in HTS and HCS, however, remains a challenge (Rimann and Graf-Hausner, 2012; Edmondson et al., 2014; Montanez-Sauri et al., 2015; Ryan et al., 2016).”