RNA-mediated non-mendelian inheritance of an epigenetic change in the mouse

By M. Rassoulzadegan, V. Grandjean, P. Gounon, S. Vincent, I. Gillot, F. Cuzin. Nature, 2006

891 citations recorded by the source corpus.

Subfields: Cancer Research, Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/b73b335756b8d332d59f3bbef72f13d38d614dc9

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Citations in the corpus

Paternally-induced transgenerational environmental reprogramming of metabolic gene expression in mammals (2010, background): “…of cytosine methylation changes at the Ppara enhancer in sperm, leads us to consider alternative epigenetic information carriers including RNA (Rassoulzadegan et al., 2006;Wagner et al., 2008) and chromatin (Arpanahi et al., 2009; Brykczynska et al., 2010; Hammoud et al., 2009; Ooi and…”
Plastics Derived Endocrine Disruptors (BPA, DEHP and DBP) Induce Epigenetic Transgenerational Inheritance of Obesity, Reproductive Disease and Sperm Epimutations (2013, background): “Demonstration of epigenetic transgenerational inheritance in worms [116], flies [117], plants [118] and mammals [119,120,121] suggest this phenomena will likely be critical in biology and disease etiology [1].”
Epigenetics and the biological definition of gene x environment interactions. (2010, background): “…bacteria, or antibodies from maternal circulation to that of the offspring, and so on (Bettegowda & Smith, 2007; Boulinier & Staszewski, 2008; Chong & Whitelaw, 2004; Grindstaff, Brodie, & Ketterson, 2003; Hasselquist & Nilsson, 2009; Rassoulzadegan et al., 2006; Shorter & Lindquist, 2005).”
Transgenerational Epigenetic Inheritance: Prevalence, Mechanisms, and Implications for the Study of Heredity and Evolution (2009, positive): “…in heterozygotes for a variant Kit gene) is known to be mediated through microRNAs with sequences partially complementary to that of Kit RNA (Rassoulzadegan et al. 2006; see supplementary material for details, available online at The Quarterly Review of Biology homepage, www…”
Nongenetic Inheritance and Its Evolutionary Implications (2009, background): “Parental environment can also affect offspring phenotype through the transfer of substances (such as hormones, proteins, lipids, RNA) via the gamete membranes or cytoplasm, or via transfer of parental soma, hormones, food-derived substances, waste-products and even parasites or symbionts .”
Transgenerational Epigenetic Inheritance: myths and mechanisms (2014, neutral): “The best known is the murine Kit allele (Rassoulzadegan et al., 2006), whereby a LacZ insertion at the Kit locus produces a Kit-LacZ fusion (resulting in nonfunctional Kit protein) that leads to melanocyte defects.”