AMPK signalling in health and disease.

By David Carling. Current Opinion in Cell Biology, 2017

701 citations recorded by the source corpus.

Subfields: Endocrinology, Diabetes and Metabolism, Molecular Biology, Surgery

View Paper: https://www.semanticscholar.org/paper/5e23d08f82654137ff4699ca151d7ccacb6e142c

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Endocrinology, Diabetes and Metabolism

1. S. Hawley
2. D. Hardie

In Molecular Biology

1. D. Hardie
2. S. Hawley
3. Yunwei Wang
4. R. Shaw
5. G. Steinberg
6. David Carling
7. K. Guan
8. Bruce E. Kemp

In Surgery

1. D. Hardie
2. S. Hawley
3. R. Shaw
4. G. Steinberg
5. K. Guan
6. Bruce E. Kemp
7. David Carling
8. David M. Sabatini

Citations in the corpus

• Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK (2017, positive): “Aldolases may be ideal sensors of glucose availability because they are not saturated with FBP at normal glucose concentrations, so that FBP availability can be sensed across the entire physiological range (Supplementary Note 3).”
• Regulation of SIRT1 and Its Roles in Inflammation (2022, background): “AMPK Promotes SIRT1 Activity AMP-activated protein kinase (AMPK) is an energy sensor protein kinase which can monitor changes in the level of ATP and directly phosphorylate metabolic enzymes to act as a key regulator in energy metabolism (69).”