EcoScale, a semi-quantitative tool to select an organic preparation based on economical and ecological parameters

By Koen Van Aken, L. Strekowski,, L. Patiny. Beilstein Journal of Organic Chemistry, 2006

597 citations recorded by the source corpus.

A novel post-synthesis analysis tool is presented which evaluates quality of the organic preparation based on yield, cost, safety, conditions and ease of workup/purification. The proposed approach is based on assigning a range of penalty points to these parameters. This semi-quantitative analysis can easily be modified by other synthetic chemists who may feel that some parameters should be assigned different relative penalty points. It is a powerful tool to compare several preparations of the same product based on safety, economical and ecological features.

Subfields: Control and Systems Engineering, Environmental Chemistry, Organic Chemistry

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