[Cerebellar cognitive affective syndrome].

By L. Garriga-Grimau, Gemma Aznar Lain, María T Nascimiento, Araitz Petrizan Aleman. Archivos Argentinos de Pediatria, 2015

841 citations recorded by the source corpus.

INTRODUCTION The diagnosis of Cerebellar Cognitive Affective Syndrome should be considered in patients with cerebellar lesions who also suffer cognitive deficits associated with visuospatial or executive neuropsychological disorders, expressive language disorders and affective disorders. CLINICAL CASE A 16 year old adolescent diagnosed with Attention Deficit Hyperactivity Disorder at the age of 7 presents with emotional instability, apathy, and speech and reading difficulties. Neuropsychological tests show visuospatial difficulties. A brain magnetic resonance imaging is performed due to impaired coordination and fine motor movements and shows atrophy of the cerebellar vermis. The clinical picture suggests a diagnosis of Cerebellar Cognitive Affective Syndrome. The cerebellum is mostly known for its motor role. However, it is also involved in higher cognitive functions, expression of emotion and behavioral regulation. Cerebellar Cognitive Affective Syndrome is a relatively unknown diagnosis and should be included in the differential diagnosis of neuropsychiatric disorders with cerebellar lesion.

Subfields: Endocrine and Autonomic Systems, Neurology, Pulmonary and Respiratory Medicine

View Paper: https://www.semanticscholar.org/paper/b59fcf3328a7d60ae2577ff41742f95cafcedc89

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In Endocrine and Autonomic Systems

In Neurology

In Pulmonary and Respiratory Medicine

Randy L. Buckner

Citations in the corpus

Consensus Paper: The Cerebellum's Role in Movement and Cognition (2013, background): “The literature indicates that behavioural deficits observed in SCAs are suggestive of a disruption of the cerebellar modulation of the neural circuits that link prefrontal, posterior parietal, superior temporal and limbic cortices [55].”
TRIPLE REPRESENTATION OF LANGUAGE, WORKING MEMORY, SOCIAL AND EMOTION PROCESSING IN THE CEREBELLUM: CONVERGENT EVIDENCE FROM TASK AND SEED-BASED RESTING-STATE FMRI ANALYSES IN A SINGLE LARGE COHORT (2018, background): “…has been supported by functional neuroimaging (Lane et al., 1997; Schraa-Tam et al., 2012; Baumann and Mattingley, 2012), TMS (Schutter et al., 2009; Schutter and Van Honk, 2009; Moulton et al., 2010) and clinical studies (Schmahmann and Sherman, 1998; Schmahmann et al, 2007; Turner et al., 2007).”
The cerebellum and cognitive function: 25 years of insight from anatomy and neuroimaging. (2013, result): “The concept of dysmetria of thought has been expanded considerably in recent years with observations of patients with cerebellar abnormalities (e.g., Schmahmann and Sherman, 1998; Tavano et al., 2007; Schmahmann, 2010) and psychosis (e.g., Andreasen et al., 1998).”