Cuproptosis: a copper-triggered modality of mitochondrial cell death

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Copper metabolism in cell death and autophagy (2023, background): “This type of cell death depends on impaired mitochondrial respiration and subsequent mitochondrial protein stress, rather than mitochondrial oxidative stress [160].”
Cuproptosis: mechanisms and links with cancers (2023, background): “As the concept of cuproptosis was introduced, a large number of publications in the form of research highlight described it [1, 2].”
Targeting cell death pathways for cancer therapy: recent developments in necroptosis, pyroptosis, ferroptosis, and cuproptosis research (2022, background): “Cuproptosis in proliferation and metastasis Cuproptosis, a Cu-induced cell death pathway, is highly associated with the mitochondrial metabolism [140] and plays a critical role in tumor cell proliferation, metastasis, and drug resistance [141, 142].”