Organic chemistry as a language and the implications of chemical linguistics for structural and retrosynthetic analyses.

By Andrea Cadeddu, Elizabeth K Wylie, J. Jurczak, M. Wampler-Doty, B. Grzybowski. 2014

84 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Computer-Assisted Retrosynthesis Based on Molecular Similarity (2017, unknown): “Cadeddu et al. 27 treat retrosynthesis in terms of chemical linguistics, where the rarest bonds are proposed as the sites of disconnections.”
Artificial intelligence in drug discovery: recent advances and future perspectives (2021, background): “This line of research is motivated by the observation that the rank distribution of fragments in organic molecules is similar to that of words in the English language [169].”
“Found in Translation”: predicting outcomes of complex organic chemistry reactions using neural sequence-to-sequence models (2017, background): “Cadeddu et al. [10] showed that organic molecules contain fragments whose rank distribution is essentially identical to that of sentence fragments.”