Adverse effects of the classic antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/nitrosative stress.
By Y. Sautin, T. Nakagawa, Sergey I Zharikov, Richard J. Johnson. American Journal of Physiology - Cell Physiology, 2007
785 citations recorded by the source corpus.
Subfields: Nephrology, Pharmacology, Rehabilitation
View Paper: https://www.semanticscholar.org/paper/b474c7e1a2a25bd44509ce4426d2d1287f772fbc
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In Nephrology
In Pharmacology
Citations in the corpus
- Sugar, Uric Acid, and the Etiology of Diabetes and Obesity (2013, background): “Incubation of cultured insulin-secreting islet cells with uric acid also causes oxidative stress and synthesis of MCP-1 (5).”
- Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease. (2007, background): “For example, uric acid stimulates both vascular smooth muscle cell proliferation and the release of chemotactic and inflammatory substances (60–62), induces monocyte chemotaxis (63), inhibits endothelial cell proliferation and migration (64, 65), and causes oxidative stress in adipocytes, which resu”