The influence of puberty on subcortical brain development
By Anne-Lise Goddings, Kathryn L. Mills, Liv S. Clasen, Jay N. Giedd, Russell M. Viner, Sarah-Jayne Blakemore. NeuroImage, 2014
464 citations recorded by the source corpus.
Puberty is characterized by hormonal, physical and psychological transformation. The human brain undergoes significant changes between childhood and adulthood, but little is known about how puberty influences its structural development. Using a longitudinal sample of 711 magnetic resonance imaging scans from 275 individuals aged 7–20 years, we examined how subcortical brain regions change in relation to puberty. Our regions of interest included the amygdala, hippocampus and corpus striatum including the nucleus accumbens (NA), caudate, putamen and globus pallidus (GP). Pubertal development was significantly related to structural volume in all six regions in both sexes. Pubertal development and age had both independent and interactive influences on volume for the amygdala, hippocampus and putamen in both sexes, and the caudate in females. There was an interactive puberty-by-age effect on volume for the NA and GP in both sexes, and the caudate in males. These findings suggest a significant role for puberty in structural brain development.
Subfields: Behavioral Neuroscience, Experimental and Cognitive Psychology, Reproductive Medicine
View Paper: https://www.semanticscholar.org/paper/b45aef081eab0d9c3c92f046ce14bdbafb9106b1
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In Behavioral Neuroscience
In Experimental and Cognitive Psychology
- Richard J. Davidson
- Kathryn L. Mills
- Eveline A. Crone
- Anne-Lise Goddings
- Sarah-Jayne Blakemore
- Ronald E. Dahl
- K. Rudolph
- Elizabeth A. Shirtcliff
In Reproductive Medicine
Citations in the corpus
- Structural brain development between childhood and adulthood: Convergence across four longitudinal samples (2016, background): “, 2012), and other studies opting to analyze the raw volumes of brain structures (Goddings et al., 2013; Raznahan et al., 2011; Wierenga et al., 2014a), and some studies reporting both (Dennison et al.”
- Behavior Problems After Early Life Stress: Contributions of the Hippocampus and Amygdala (2014, background): “, 5–15 years old); this is particularly important to note because amygdala development appears to be nonlinear in nature (63,64).”