Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets.

By Bharat B. Aggarwal, Bokyung Sung. TIPS - Trends in Pharmacological Sciences, 2009

1,125 citations recorded by the source corpus.

Subfields: Molecular Biology, Molecular Medicine

View Paper: https://www.semanticscholar.org/paper/b4572b197bb3d5c7fed88d11395854ab09666aa3

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Citations in the corpus

TNF and TNF-receptors: From mediators of cell death and inflammation to therapeutic giants - past, present and future. (2014, background): “Curcumin is a naturally produced compound that inhibits TNF and other pro-inflammatory cytokines including TNF, IL-1b and IL-6; it is a broad-acting anti-TNF and anti-inflammatory nutraceutical, generally consumed orally via natural food spices and/or via medicinal preparations (for reviews see [184”
Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases (2017, background): “…various cytokines, such as TNF-α, IL-1, IL-6, IL-8, IL-12, monocyte chemoattractant protein (MCP)-1 (also known as CCL2) and IL-1β, and various inflammatory enzymes and transcription factors (Bharti et al., 2004; Davis et al., 2007; Aggarwal and Sung, 2009; Gupta et al., 2011a; 2014).”
American Cancer Society guidelines on nutrition and physical activity for cancer prevention (2002, background): “Do turmeric and other spices reduce cancer risk? Research is currently underway evaluating turmeric’s effect on cancer suppression.(366) Other spices also being investigated to determine possible anticancer effects include capsaicin (red pepper), cumin, and curry.”
Herbal extracts and phytochemicals: plant secondary metabolites and the enhancement of human brain function. (2011, background): “To the present, over 40 small pilot trials in humans have been completed assessing pharmacodynamics/kinetics and efficacy in a variety of small patient groups (217).”