Immune self-reactivity triggered by drug-modified HLA-peptide repertoire

By P. Illing, J. Vivian, N. Dudek, L. Kostenko, Zhenjun Chen, M. Bharadwaj, John J Miles, L. Kjer-Nielsen, S. Gras, N. Williamson and 4 more. Nature, 2012

674 citations recorded by the source corpus.

Subfields: Pharmacology, Physiology, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/b432b53868b690cee45ef4cd06972b14856e9833

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In Radiology, Nuclear Medicine and Imaging

1. Yeeleng Scott Vang
2. Xiaohui S. Xie

Citations in the corpus

• HLA class I binding prediction via convolutional neural networks (2017, background): “…the importance of binding, accurate prediction models can shed understanding to adverse drug reactions and autoimmune diseases [Gebe et al ., the 2002, Illing et al ., 2012], and lead to the de-sign of more effective protein therapy and vaccines [Chirino et al ., 2004, van der Burg et al ., 2006].”
• Major Histocompatibility Complex Genomics and Human Disease (2013, neutral): “A crystal structure of abacavir in combination with HLA-B∗57:01 with peptide showed that the drug noncovalently binds to the class I molecule (55).”