Airway structural alterations selectively associated with severe asthma.

By L. Benayoun, A. Druilhe, M. Dombret, M. Aubier, M. Pretolani. American Journal of Respiratory and Critical Care Medicine, 2003

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Eosinophils: Biological Properties and Role in Health and Disease (2008, background): “The clinical significance of these findings is unclear, especially as fibroblast accumulation and airway smooth muscle cell hypertrophy in proximal airways seem to be more selective determinants of severe persistent asthma than matrix deposition beneath the basement membrane (Benayoun et al. 2003).”