Alternatives for large-scale production of cultured beef: A review
By Matilda S M Moritz, S. Verbruggen, M. Post. 2015
115 citations recorded by the source corpus.
Cultured beef is a method where stem cells from skeletal muscle of cows are cultured in vitro to gain edible muscle tissue. For large-scale production of cultured beef, the culture technique needs to become more efficient than today's 2-dimensional (2D) standard technique that was used to make the first cultured hamburger. Options for efficient large-scale production of stem cells are to culture cells on microcarriers, either in suspension or in a packed bed bioreactor, or to culture aggregated cells in suspension. We discuss the pros and cons of these systems as well as the possibilities to use the systems for tissue culture. Either of the production systems needs to be optimized to achieve an efficient production of cultured beef. It is anticipated that the optimization of large-scale cell culture as performed for other stem cells can be translated into successful protocols for bovine satellite cells resulting in resource and cost efficient cultured beef.
Subfields: Biomedical Engineering, Molecular Biology, Surgery
View Paper: https://www.semanticscholar.org/paper/b3e808bff195b4c7202d77dad1c1a53423c5f455
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In Biomedical Engineering
In Molecular Biology
Citations in the corpus
- Tissue Engineering for Clean Meat Production (2019, background): “Customized bioreactors need to be developed and optimized for clean meat production, to improve the efficiency of media use, and recycle main media components (Moritz et al., 2015; Specht et al., 2018; Stephens et al., 2018a).”