Overcoming the blood-brain tumor barrier for effective glioblastoma treatment.

By O. Tellingen, B. Yetkin-Arik, M. C. Gooijer, P. Wesseling, T. Wurdinger, H. D. Vries. Drug resistance updates, 2015

921 citations recorded by the source corpus.

Subfields: Cell Biology, Genetics, Oncology

View Paper: https://www.semanticscholar.org/paper/b3448233fdeca3d43b49e0c87f84a5df90f9a6de

How researchers see this paper

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In Genetics

1. Xiaowei Dong

In Oncology

1. Xiaowei Dong

Citations in the corpus

• Functional morphology of the blood-brain barrier in health and disease (2018, neutral): “Although intrinsic resistance mechanisms to anti-angiogenic therapy have been identified, unsuccessful drug delivery across the BBB may contribute to inefficient therapy [128].”
• Current Challenges and Opportunities in Treating Glioblastoma (2018, background): “Although this may suggest that small molecules may be more permeable at the tumor site, the BBB surrounding the proliferating cells at the tumor’s edge remains intact (van Tellingen et al., 2015).”
• Current Strategies for Brain Drug Delivery (2018, background): “BBTB permeability in glioblastomas is high in bulk tumor areas, but slight or null in peripheral regions [16].”