Associative learning mediates dynamic shifts in dopamine signaling in the nucleus accumbens

By J. Day, M. Roitman, R. Wightman, Regina M. Carelli. Nature Neuroscience, 2007

705 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/b342b109a9513e81dfe0702bde8bd0e5296200b6

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Citations in the corpus

Imaging dopamine's role in drug abuse and addiction. (2009, positive): “These effects mimic but surpass the DA increases secondary to phasic DA cell firing that play a physiological role in coding for saliency and reward (Schultz et al., 2000).”
Updating dopamine reward signals (2013, background): “It leads to dopamine release in rats [54].”
Dopamine in motivational control: rewarding, aversive, and alerting (2010, methodology): “Computational models using a TD-like reinforcement signal can explain many aspects of reinforcement learning in humans, animals, and DA neurons themselves (Sutton and Barto, 1981; Waelti et al., 2001; Montague and Berns, 2002; Dayan and Niv, 2008).”
Midbrain dopamine neurons signal preference for advance information about upcoming rewards (2009, background): “This nonspecific response is probably due to the animal’s initial uncertainty about the stimulus identity (Kakade and Dayan, 2002; Day et al., 2007) or stimulus timing (Fiorillo et al.”
Reinforcement learning in the brain (2009, background): “Finally, measurements of extracellular dopamine in behaving rodents using fast scan cyclic voltammetry have confirmed that phasic changes in the level of dopamine in target structures (specifically, in the striatum) also conform quantitatively to a prediction error signal (Paul Phillips, personal co”
The nucleus accumbens: an interface between cognition, emotion, and action. (2015, background): “Thus, the A cce clearly contributes to discriminative and volitional control of approach, but its involvement appears to be most prominent when there is considerable ambiguity regarding the appropriate course of action for procurement of rewards. stimuli.”
Activation of VTA GABA neurons disrupts reward consumption (2012, neutral): “In addition, exposure to cues that predict natural rewards or drugs of abuse lead to transient surges in dopamine release in the nucleus accumbens (NAc) (Day et al., 2007; Phillips et al., 2003; Roitman et al., 2004; Stuber et al., 2008; Stuber et al., 2005).”
Decision theory, reinforcement learning, and the brain (2008, background): “…phasic activity of dopamine cells in the ventral tegmental area (VTA) and substantia nigra pars compacta (SNc) in monkeys (eg Schultz, 2002), and the release of dopamine at striatal targets in rats (Day et al., 2007) report quantities akin to the temporal difference prediction error in equation 7.”