Optical Imaging Techniques for Point-of-care Diagnostics

By Hongying Zhu, S. Isikman, O. Mudanyali, A. Greenbaum, Aydogan Ozcan. Lab on a Chip, 2012

343 citations recorded by the source corpus.

Improving the access to effective and affordable healthcare has long been a global endeavor. In this quest, the development of cost-effective and easy-to-use medical testing equipment that enable rapid and accurate diagnosis is essential to reduce the time and costs associated with healthcare services. To this end, point-of-care (POC) diagnostics plays a crucial role in healthcare delivery in both the developed and developing countries by bringing medical testing to patients, or to sites near patients. As the diagnosis of a wide range of diseases, including various types of cancers and many endemics relies on optical techniques, numerous compact and cost-effective optical imaging platforms have been developed in recent years for use at the POC. Here, we review the state-of-the-art optical imaging techniques that can have significant impact on global health by facilitating effective and affordable POC diagnostics.

Subfields: Biomedical Engineering, Clinical Biochemistry, Ophthalmology

View Paper: https://www.semanticscholar.org/paper/b2a9c6a8bf0547aaf5129e14ae7d5b87795f9b1b

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In Biomedical Engineering

Citations in the corpus

Critical review on biofilm methods (2017, methodology): “Optical detection methods are often employed (Meyer et al., 2011; Zhu et al., 2013) in particular fluorescence (Johnson & Landers, 2004).”
Advances in paper-based point-of-care diagnostics. (2014, background): “A recent review has detailed the use of mobile phone based techniques for POC diagnostics (Zhu et al., 2013).”
Small but Perfectly Formed? Successes, Challenges, and Opportunities for Microfluidics in the Chemical and Biological Sciences (2017, background): “These include the assimilation of electrochemical detectors(54) and integration of smartphone cameras for readout given their ubiquitous nature even in developing countries.(55) Paper-based microfluidic devices uniquely offer the potential for truly disposable, self-contained, and low-cost diagnosti”