Measuring conformational dynamics of biomolecules by single molecule fluorescence spectroscopy

By Shimon Weiss. Nature Structural Biology, 2000

648 citations recorded by the source corpus.

Subfields: Biophysics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/b2807c9a6db0555f9b9dceca19c965935d3dc679

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biophysics

1. Alexander Johnson-Buck
2. Peng Sang
3. J. Zavislan
4. G. Bonnet
5. Lukás Novotný
6. N. Walter
7. M. Lieb
8. Xing Du

In Molecular Biology

1. Alexander Johnson-Buck
2. Peng Sang
3. J. Zavislan
4. G. Bonnet
5. Lukás Novotný
6. N. Walter
7. M. Lieb
8. Xing Du

Citations in the corpus

• Fluorescence correlation spectroscopy: the technique and its applications (2002, background): “…of techniques have emerged which allow one to detect and manipulate single biological molecules (for reviews see Xie and Trautman (1998), Mehta et al (1999), Schmidt et al (1999), Weiss (1999, 2000), Xie and Lu (1999), Clausen-Schaumann et al (2000), Strick et al (2000), Yanagida et al (2000)).”
• Single-molecule orientations determined by direct emission pattern imaging (2004, methodology): “Whereas the calculation of aberrated or defocused images of a single dipole emitter involves the solution of rather complicated Fresnel integrals,28 the calculation of the emission pattern in the back-aperture plane according to Proportion (1) and Eqs.”
• Insights into Protein–Ligand Interactions: Mechanisms, Models, and Methods (2016, methodology): “Other experimental methods that have been applied to study the protein dynamics involved in binding include single-molecule fluorescence spectroscopy [104] and time-resolved hydrogen-deuterium exchange mass spectrometry [105].”
• Near-wall hindered Brownian diffusion of nanoparticles examined by three-dimensional ratiometric total internal reflection fluorescence microscopy (3-D R-TIRFM) (2004, background): “Single molecule detection (SMD) techniques to visualize the dynamic behavior and reaction kinetics of individual molecules in living cells have recently attracted a great deal of attention (Xie 2001; Weiss 2000).”
• Stochastic modeling in nanoscale biophysics: Subdiffusion within proteins (2008, background): “…study biological processes on an unprecedented nanoscale molecule-by-molecule basis [cf. Moerner (2002), Nie and Zare (1997), Tamarat, Maali, Lounis and Orrit (2000), Weiss (2000), Xie and Lu (1999), Xie and Trautman (1998), Kou, Xie and Liu (2005)], thus Received June 2007; revised October 2007.”
• Bayesian analysis of single‐molecule experimental data (2005, background): “…to make observations on single-molecule dynamics, which was unthinkable just a few decades ago (Nie and Zare, 1997; Xie and Trautman, 1998; Weiss, 2000; Tamarat et al., 2000; Moerner, 2002)—the famous physicist Richard Feynman once described that seeing the images of single atoms was a…”
• A BIRD’S EYE VIEW: TRACKING SLOW NANOMETER-SCALE MOVEMENTS OF SINGLE MOLECULAR NANO-ASSEMBLIES (2010, positive): “…particularly powerful tool to probe distances (Deniz et al., 1999; Ha et al., 1996; Stryer and Haugland, 1967), conformational changes (Kim et al., 2002; Truong and Ikura, 2001; Weiss, 2000), and dynamics (Al-Hashimi and Walter, 2008; Zhuang et al., 2002) of macromolecules on the order of 1–10 nm.”