Lab-on-a-chip: microfluidics in drug discovery

By Petra S. Dittrich, Andreas Manz. Nature reviews. Drug discovery, 2006

1,753 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/b1c204a6326599e1815abead80031056419b86cb

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biomedical Engineering

Citations in the corpus

3D printing: an emerging tool for novel microfluidics and lab-on-a-chip applications (2016, positive): “…(LOC) technologies have been revolutionizing many fields such as medicine, chemistry, and biotechnologies (Barry and Ivanov 2004; Beebe et al. 2002; Dittrich and Manz 2006; Hong and Quake 2003; Stone et al. 2004; Thorsen et al. 2002; Wang et al. 2009; Weibel and Whitesides 2006; Whitesides 2006;…”
Two-color laser-induced fluorescent thermometry for microfluidic systems (2008, background): “For instance, precision control of fluid temperature by accounting for local temperature gradients could optimize chemical operations such as mixing, reactions and separations within complex microfluidic systems, including lab-on-achip devices or microscale fuel cells [2, 3 ]. Such control becomes ”
Large‐scale image‐based screening and profiling of cellular phenotypes (2017, positive): “The second approach uses microfluidic devices, which are miniaturized fluidic channels (usually 1 mm) that can perform liquid handling and perturbation experiments (64,65).”
Cells on chips (2006, background): “Much cell-based microsystem research takes place under a 'lab-on-a-chip' or 'micro-total-analysis-system' (µTAS) framework that seeks to create microsystems incorporating several steps of an assay into a single syste”
PDMS-Based Microfluidic Devices for Cell Culture (2018, background): “Microfluidic cell culture has been shown to lead to an increase in the throughput of different research topics, such as experiments for drug testing [22,23].”