Role of Receptors in Bacillus thuringiensis Crystal Toxin Activity

By Craig Pigott, D. Ellar. Microbiology and Molecular Biology Reviews, 2007

701 citations recorded by the source corpus.

Subfields: Insect Science, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/b1ab21208fef92830023a84b03e0e29c2ed8f9b6

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Citations in the corpus

Microbial Biopesticides in Agroecosystems (2018, background): “Varying toxin gene sequences result in different affinity with insect midgut receptors, so that different strains are characterized by diverse insecticidal protein toxins and strain-specific insecticidal properties [10].”
Bacillus thuringiensis insecticidal three-domain Cry toxins: mode of action, insect resistance and consequences for crop protection. (2013, background): “It was reported that Cry11Aa and Cry4Ba have synergistic activity, in some cases showing up to 10- fold higher activity against mosquitoes in the mixture than the expected mortality from the individual toxins (Poncet et al., 1995; Fernandez-Luna et al., 2010).”
Insecticidal Genetically Modified Crops and Insect Resistance Management (IRM) (2008, background): “…53 3/10/2008 7:19:23 PM Un co rr ec te d Pr oo f 54 J. Ferré et al. (Griffitts et al., 2005) and glycosylated GPI-anchored alkaline phosphatase (McNall and Adang, 2003; Jurat-Fuentes and Adang, 2004; Fernández et al., 2006) have been implicated in Cry protein binding (Pigott and Ellar, 2007).”
Diversity of bacillus thuringiensis crystal toxins and mechanism of action (2014, methodology): “glycoconjugates have been proposed to contain Cry toxin-binding sites and represent functional receptors (Pigott and Ellar, 2007), most data available are focused on cadherin, APN, and ALP proteins.”
Insect pathogens as biological control agents: Back to the future. (2015, background): “Domains II and III are comprised of layers of beta sheets that recognize specific binding sites at the surface of the midgut brush border (Pigott and Ellar, 2007).”
Bacillus thuringiensis: A story of a successful bioinsecticide. (2011, background): “In contrast, APN and ALP show lower binding affinities that are in the range of more than 100 nM binding affinity (reviewed in Pigott and Ellar, 2007).”