Relationships Between Sinus Rhythm, Treatment, and Survival in the Atrial Fibrillation Follow-Up Investigation of Rhythm Management (AFFIRM) Study

By Corley Sd, A. Epstein, J. Dimarco, M. Domanski, N. Geller, Greene Hl, R. Josephson, J. Kellen, R. Klein, A. Krahn and 9 more. Circulation, 2004

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Catheter ablation of atrial fibrillation in heart failure. (2013, methodology): “Contrary to studies on catheter ablation in patients with Kirubakaran & O’Neill528 preserved LV systolic function, patients with persistent AF seemed to derive significant benefit from catheter ablation and one might argue have more to gain, because these patients are more likely to have an associat”
2012 HRS/EHRA/ECAS expert consensus statement on catheter and surgical ablation of atrial fibrillation: recommendations for patient selection, procedural techniques, patient management and follow-up, definitions, endpoints, and research trial design (2012, background): “However, a post hoc on-treatment analysis of the AFFIRM study revealed that the presence of sinus rhythm was associated with a significant reduction in mortality, whereas the use of antiarrhythmic drugs increased mortality by 49% [108], suggesting that the beneficial effect of sinus rhythm restorati”