Migrastatin analogues target fascin to block tumour metastasis
By Lin Chen, Shengyu Yang, J. Jakoncic, J. J. Zhang, Xin-Yun Huang. Nature, 2011
134 citations recorded by the source corpus.
Subfields: Cancer Research, Oncology, Spectroscopy
View Paper: https://www.semanticscholar.org/paper/b08f7d120bf22461b9c3cdaffd54b2177e79e3ba
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In Cancer Research
In Oncology
Citations in the corpus
- Tumor Metastasis: Molecular Insights and Evolving Paradigms (2011, background): “Unfortunately, however, the rationale behind many targeted agents that were designed to impair carcinoma metastasis, such as MMP inhibitors, the Axl kinase inhibitor R428, miR-10b antagonists, and the fascin inhibitor Migrastatin, is incompatible with these clinical observations, as these compounds ”