Complete mitochondrial genome sequence of a Middle Pleistocene cave bear reconstructed from ultrashort DNA fragments

By Jesse Dabney, M. Knapp, Isabelle Glocke, Marie-Theres Gansauge, A. Weihmann, B. Nickel, C. Valdiosera, N. García, Svante Pääbo, J. Arsuaga and 1 more. Proceedings of the National Academy of Sciences of the United States of America, 2013

1,367 citations recorded by the source corpus.

Subfields: Anthropology, Archeology, Genetics

View Paper: https://www.semanticscholar.org/paper/af905cf04b20825fb184b1afebfbed79194f5f1a

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Citations in the corpus

Pathways to de‐extinction: how close can we get to resurrection of an extinct species? (2017, background): “However, improvements in ancient DNA methodologies within the last several years (Dabney et al. 2013; Gansauge & Meyer 2013) have made it possible to reconstruct full genome sequences from samples preserved in an increasingly wide range of preservation environments, and full genomes are now…”
From the field to the laboratory: Controlling DNA contamination in human ancient DNA research in the high-throughput sequencing era (2017, positive): “Some DNA extraction protocols target ultra-short DNA fragments (Gamba et al. 2015; Dabney et al. 2013) or reduce the fraction of contaminating DNA through sample incubation in buffers or bleach (Der Sarkissian et al. 2014; Korlevi ć et al. 2015; Damgaard et al. 2015; Malmstrom et al. 2007; Salamon…”
Characterization of ancient and modern genomes by SNP detection and phylogenomic and metagenomic analysis using PALEOMIX (2014, methodology): “PCR amplification of DNA libraries can also result in a biased representation of DNA inserts, with size differences and GC content percentages as well-characterized sources of bias 30 .”
A high-coverage Neandertal genome from Vindija Cave in Croatia (2017, methodology): “To generate DNA suitable for deep sequencing, we extracted DNA (17) and generated DNA libraries (18) from 12 samples from Vindija 33.”
Single‐tube library preparation for degraded DNA (2017, background): “To overcome these complications in degraded samples, researchers have developed library building and PCR protocols optimized to recover small amounts of DNA and tackle chemical damage (e.g. d’Abbadie et al. 2007; Shapiro, 2008; Heyn et al. 2010; Dabney et al. 2013b; Gansauge and Meyer, 2013).”
The genetic history of Ice Age Europe (2016, background): “45 13,090-12,830 Direct-NotUF (5) Epipaleolithic Mandible 1240k M U5b2b I Villabruna No 0.”