Cardiac Troponin I Is Associated With Impaired Hemodynamics, Progressive Left Ventricular Dysfunction, and Increased Mortality Rates in Advanced Heart Failure

By T. Horwich, J. Patel, W. R. Maclellan, G. Fonarow. Circulation, 2003

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2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. (2013, background): “In chronic HF, elaboration of cardiac troponins is associated with impaired hemodynamics (238), progressive LV dysfunction (239), and increased mortality rates (238–241,276).”
Acute heart failure syndromes (2009, neutral): “3-fold increase in the rehospitalization rate (14,79).”
2017 ACC/AHA/HFSA Focused Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America. (2017, background): “Similarly, abnormal levels of circulating cardiac troponin arecommonly found inpatientswithacute decompensatedHF, oftenwithout obviousmyocardial ischemia or underlying coronary artery disease (CAD), and this is associated with worse clinical outcomes and higher risk of death (95,99,102,103).”