The entry of nanoparticles into solid tumours

By Shrey Sindhwani, A. Syed, Jessica Ngai, Benjamin R. Kingston, L. Maiorino, J. Rothschild, Presley MacMillan, Yuwei Zhang, N. U. Rajesh, Tran Hoang and 10 more. Nature Materials, 2020

1,364 citations recorded by the source corpus.

Subfields: Biomaterials, Biomedical Engineering, Electronic, Optical and Magnetic Materials

View Paper: https://www.semanticscholar.org/paper/ae8c4faeed52dd5550b7cfa7491c75a047912d31

How researchers see this paper

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In Biomaterials

1. Jun Wu

In Biomedical Engineering

1. Xiaoyuan Chen
2. Jun Wu
3. T. Lammers

In Electronic, Optical and Magnetic Materials

1. Xiaoyuan Chen

Citations in the corpus

• The EPR effect and beyond: Strategies to improve tumor targeting and cancer nanomedicine treatment efficacy (2020, background): “It has been demonstrated that the mechanism by which nanoparticles enter solid tumors is more complex than previously thought (potentially going beyond simple extravasation through gaps in the endothelial lining) [7], and that immune cells in the tumor microenvironment play important roles in nanome”
• The Enhanced Permeability and Retention (EPR) Effect: The Significance of the Concept and Methods to Enhance Its Application (2021, background): “Recent studies have found that the gaps between endothelial cells in tumor vessels are at low frequency, and the transendothelial pathways are the dominant mechanism of nanoparticle extravasation in tumors [17].”