Immobilization Techniques in the Fabrication of Nanomaterial-Based Electrochemical Biosensors: A Review
By Will Putzbach, Niina J. Ronkainen. Italian National Conference on Sensors, 2013
433 citations recorded by the source corpus.
The evolution of 1st to 3rd generation electrochemical biosensors reflects a simplification and enhancement of the transduction pathway. However, in recent years, modification of the transducer with nanomaterials has become increasingly studied and imparts many advantages. The sensitivity and overall performance of enzymatic biosensors has improved tremendously as a result of incorporating nanomaterials in their fabrication. Given the unique and favorable qualities of gold nanoparticles, graphene and carbon nanotubes as applied to electrochemical biosensors, a consolidated survey of the different methods of nanomaterial immobilization on transducer surfaces and enzyme immobilization on these species is beneficial and timely. This review encompasses modification of enzymatic biosensors with gold nanoparticles, carbon nanotubes, and graphene.
Subfields: Electrical and Electronic Engineering, Electrochemistry, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/ae45b9cce9fc9fb89d9973260e1170aec67aff99
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Citations in the corpus
- Nanomaterials for biosensing applications: a review (2014, methodology): “Efficient methods for the biofunctionalization of nanomaterials are summarized in reference (Putzbach and Ronkainen, 2013).”
- Laccase-based biosensors for detection of phenolic compounds (2015, background): “Incorporation of nanomaterials has been demonstrated to improve sensitivity and overall performance of enzymatic biosensors, especially with AuNPs, CNTs and graphene [143].”