Mechanisms of Drug Resistance in Cancer Chemotherapy

By Y. Luqmani. Medical Principles and Practice, 2005

636 citations recorded by the source corpus.

Subfields: Molecular Biology, Oncology, Pharmacology

View Paper: https://www.semanticscholar.org/paper/ad895f63cd8ae09e0ca53afae9c2d6b17710cec1

How researchers see this paper

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In Molecular Biology

1. Huanhuan Chen
2. Li-li Zheng
3. Zhenling Liu
4. Li-Ping Sun
5. Lei Shi
6. Y. Lee

Citations in the corpus

• Angiogenic signaling pathways and anti-angiogenic therapy for cancer (2023, background): “Even so, tumor cells are not entirely killed, drug resistance rises unavoidably.(31,32) Prior works have demonstrated that congenital and acquired drug resistance can be derived from tumor genetic and phenotypic mutations.”
• Cancer Stem Cells (CSCs) in Drug Resistance and their Therapeutic Implications in Cancer Treatment (2018, background): “However, chemotherapy induces tumor heterogeneity derived from both normal and cancer cells and the heterogeneity within tumors, in turn, results in reducing effects of chemotherapy; contributing to the treatment failure and disease progression [5, 6].”
• Mechanisms of Multidrug Resistance in Cancer Chemotherapy (2020, background): “Because the drug concentration is limited, at some point, it is not able to inhibit the increased amount of enzyme [9,44].”