Increase in Suicide in the United States, 1999-2014.

By S. Curtin, M. Warner, H. Hedegaard. NCHS data brief, 2016

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The effect of a single dose of intravenous ketamine on suicidal ideation: a systematic review and individual participant data meta-analysis (2017, unknown): “Unfortunately, the suicide rate has increased over the past twodecades despite renewed efforts to address this crisis (3).”
Tobacco Product Use Among Adults — United States, 2017 (2018, background): “Primary reasons for e-cigarette use among adults include curiosity, flavoring, cost, consideration of others, convenience, and simulation of cigarettes, as well as to attempt to quit smoking (6).”
Traumatic Brain Injury–Related Emergency Department Visits, Hospitalizations, and Deaths — United States, 2007 and 2013 (2017, background): “The increase in fatal TBIs attributable to intentional self-harm is consistent with an overall increase in suicide rates in the United States and underscores the importance of comprehensive and coordinated prevention efforts, including efforts to enhance social support and connectedness, reduce stig”
Ethical Research Protocols for Social Media Health Research (2017, background): “Similarly, insufficient research results in a cost measured in human lives – in the United States, more than 40,000 die from suicide each year (Curtin et al., 2016).”