Highly enantioselective conjugate addition of nitromethane to chalcones using bifunctional cinchona organocatalysts.

By Benedek Vakulya, S. Varga, A. Csámpai, T. Soós. Organic Letters, 2005

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Cinchona alkaloid-derived chiral bifunctional thiourea organocatalysts were synthesized and applied in the Michael addition between nitromethane and chalcones with high ee and chemical yields.

Subfields: Organic Chemistry

View Paper: https://www.semanticscholar.org/paper/ac4fae4ff4febcd4c02a26471e5d41eb62b20a62