Superinfection immunity of mycobacteriophage L5: applications for genetic transformation of mycobacteria

By M. Donnelly‐Wu, W. Jacobs, Graham F. Hatfull. 1993

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Transcriptional regulation and immunity in mycobacteriophage Bxb1 (2000, background): “Mycobacteriophage L5 is a temperate phage of the mycobacteria that uses a very different immunity system from that of the lambda-like phages (Donnelly-Wu et al., 1993; Hatfull, 1994; 1999; Nesbit et al., 1995; Brown et al., 1997).”
Evolution of Superinfection Immunity in Cluster A Mycobacteriophages (2019, background): “Cluster A Rep similarly has an N-terminal helix-turn-helix DNA-binding domain (16, 24) and a distinct C-terminal region (27).”
An Unusual Phage Repressor Encoded by Mycobacteriophage BPs (2015, background): “For example, the repressor of Streptomyces phage φC31 is located downstream of the virion structural genes and is similarly transcribed rightwards [6, 7], and in mycobacteriophage L5 (and its relatives) the repressor is located within the right arm of the genome and transcribed leftwards along with ”
Transcriptional silencing by the mycobacteriophage L5 repressor (1997, background): “…by Southern hybridization.and 119 bp fragments that contain binding sites 1 and 2 respectively, (iv) a derivative of the 222 bp fragment generated by cutting and filling pMD132 (Donnelly-Wu et al., 1993) is an extrachromosomal shuttle plasmid containing L5 gene 71 and its regulatory sequences.”