The AGAMOUS-LIKE 20 MADS domain protein integrates floral inductive pathways in Arabidopsis.

By Horim Lee, S. Suh, Eunsook Park, Eun Cho, J. Ahn, Sang-Gu Kim, Jong Seob Lee, Y. Kwon, I. Lee. Genes & Development, 2000

752 citations recorded by the source corpus.

The very late-flowering behavior of Arabidopsis winter-annual ecotypes is conferred mainly by two genes, FRIGIDA (FRI) and FLOWERING LOCUS C (FLC). A MADS-domain gene, AGAMOUS-LIKE 20 (AGL20), was identified as a dominant FRI suppressor in activation tagging mutagenesis. Overexpression of AGL20 suppresses not only the late flowering of plants that have functional FRI and FLC alleles but also the delayed phase transitions during the vegetative stages of plant development. Interestingly, AGL20 expression is positively regulated not only by the redundant vernalization and autonomous pathways of flowering but also by the photoperiod pathway. Our results indicate that AGL20 is an important integrator of three pathways controlling flowering in Arabidopsis.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/ac37d7331f7c6d7d39c2713f1567e70b29894e48

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In Molecular Biology

1. G. Coupland
2. Detlef Weigel
3. M. Hanke
4. F. Fornara
5. L. Corbesier
6. F. Turck
7. P. Achard
8. C. Dean

In Plant Science

1. Detlef Weigel
2. G. Coupland
3. Stephan Ossowski
4. R. Schwab
5. M. Hanke
6. F. Fornara
7. L. Corbesier
8. F. Turck

Citations in the corpus

• Highly Specific Gene Silencing by Artificial MicroRNAs in Arabidopsis[W][OA] (2006, methodology): “…et al., 2001; Ratcliffe et al., 2003), and floral activators, such as SUPPRESSOR OF OVEREXPRESSION OF CONSTANS1 (SOC1) (Borner et al., 2000; Lee et al., 2000; Samach et al., 2000), as well as ARABIDOPSIS NITRATE REGULATED1 (ANR1), which is involved in nutrient uptake (Zhang and Forde,…”
• No Flower no Fruit - Genetic Potentials to Trigger Flowering in Fruit Trees (2007, background): “Isolation and characterization of native floral pathway integrators Considerably more is known about genes which are puta- tive homologs of the floral pathway integrators LFY, FT and SOC1.”
• Multiple Pathways in the Decision to Flower: Enabling, Promoting, and Resetting (2004, background): “…integrators’’ and include FLOWERING LOCUS T (FT), LEAFY (LFY), and SUPPRESSOR OF OVEREXPRESSION OF CONSTANS (SOC1), also known as AGAMOUS-LIKE 20 (AGL20) (Nilsson et al., 1998; Kardailsky et al., 1999; Kobayashi et al., 1999; Blázquez andWeigel, 2000; Lee et al., 2000; Samach et al., 2000).”
• Photoperiodic flowering of Arabidopsis: integrating genetic and physiological approaches to characterization of the floral stimulus (2005, background): “FT encodes a protein with similarity to RAF kinase inhibitors of animals (Kardailsky et al. 1999; Kobayashi et al. 1999) whereas SOC1 encodes a MADS box transcription factor (Borner et al. 2000; Lee et al. 2000; Samach et al. 2000).”
• Control of flowering time: interacting pathways as a basis for diversity. (2002, background): “In addition, FT and SOC1 expression levels are increased in 35S :: CO plants or 35S :: CO : GR plants in which CO activity is induced by dexamethasone (Samach et al., 2000), indicating that these genes act downstream of CO .”
• Regulation and identity of florigen: FLOWERING LOCUS T moves center stage. (2008, background): “SOC1 acts as a floral integrator and is activated by FT-dependent and FT-independent pathways (50, 65, 77, 100).”
• Modulation of floral development by a gibberellin-regulated microRNA (2004, background): “microRNA”
• miR156-regulated SPL transcription factors define an endogenous flowering pathway in Arabidopsis thaliana. (2009, neutral): “…have shown that SOC1 , FUL , and AGL24 all function downstream of CONSTANS (CO), the output of the photoperiod pathway, which accelerates flowering of A. thaliana in long days (Borner et al., 2000; Lee et al., 2000; Melzer et al., 2008; Samach et al., 2000; Schmid et al., 2003; Yu et al., 2002).”