Prospero-related homeobox 1 gene (Prox1) is regulated by canonical Wnt signaling and has a stage-specific role in adult hippocampal neurogenesis

By Özlem Karalay, Kathrin Doberauer, K. Vadodaria, M. Knobloch, L. Berti, A. Miquelajauregui, Manuela Schwark, R. Jagasia, M. Taketo, V. Tarabykin and 4 more. 2011

204 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience, Molecular Biology

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. M. Marchetto
2. T. Toda
3. Sarah L. Parylak
4. Sara B. Linker
5. Giorgia Quadrato
6. M. Elnaggar
7. S. Di Giovanni
8. Fred H. Gage

In Developmental Neuroscience

1. M. Marchetto
2. Sarah L. Parylak
3. Sara B. Linker
4. T. Toda
5. Giorgia Quadrato
6. M. Elnaggar
7. S. Di Giovanni
8. Fred H. Gage

In Molecular Biology

1. M. Marchetto
2. Fred H. Gage
3. Hongjun Song

Citations in the corpus

• Adult neurogenesis in brain repair: cellular plasticity vs. cellular replacement (2014, background): “…Transcription factor DG Quadrato et al., 2012 NF-KappaB p50 Transcription factor DG Denis-Donini et al., 2008 CREB Transcription factor DG Jagasia et al., 2009 Neuro D1 Transcription factor DG, SVZ Gao et al., 2009 PROX1 Transcription factor DG Lavado et al., 2010; Karalay et al., 2011”
• Modeling Hippocampal Neurogenesis Using Human Pluripotent Stem Cells (2014, methodology): “After 20 days, the mature EBs were treated with Wnt3a, a WNT protein previously shown to be important for the maintenance of hippocampal progenitors and their differentiation into DG granule neurons (Lee et al., 2000; Machon et al., 2007; Kuwabara et al., 2009; Wexler et al., 2009; Karalay et al., 2”
• The role of adult hippocampal neurogenesis in brain health and disease (2018, background): “Karalay O, Doberauer K, Vadodaria KC, Knobloch M, Berti L, Miquelajauregui A, et al. Prosperorelated homeobox 1 gene (Prox1) is regulated by canonical Wnt signaling and has a stage-specific role in adult hippocampal neurogenesis.”
• Functional Imaging of Dentate Granule Cells in the Adult Mouse Hippocampus (2016, unknown): “This approach resulted in specific labeling of DG granule cells within the adult hippocampus as verified by post hoc histological staining using Prox1, a homeobox-domain transcription factor that is selectively expressed in granule cells in the adult mouse forebrain (Karalay et al., 2011; Fig.”