Risk score for the prediction of dementia risk in 20 years among middle aged people: a longitudinal, population-based study.

By Miia Kivipelto, T. Ngandu, T. Laatikainen, Bengt Winblad, Hilkka Soininen, J. Tuomilehto. Lancet Neurology, 2006

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Impact of multiple pathologies on the threshold for clinically overt dementia (2017, background): “This evidence makes it likely that the cooccurrence of CVD increases dementia risk in later life as suggested by risk factor analyses based on epidemiological studies [68], and points to potential therapeutic interventions that may substantially reduce dementia incidence through the aggressive contr”
The overlap between vascular disease and Alzheimer’s disease - lessons from pathology (2014, background): “, atrial fibrillation and congestive heart failure, have also been linked to the pathogenesis and progression of AD and are among the most important modifiable risk factors for AD [35-42].”
Education and Cognitive Functioning Across the Life Span (2020, background): “Risk indices predicting risk for dementia at middle age or later in life have been developed and validated, and education (as well as unhealthy lifestyles and cardiometabolic risk factors) is a critical factor in such indices (e.g., K. J. Anstey et al., 2014; Kivipelto et al., 2006).”