Increased expression of extracellular signal-regulated kinase and angiotensin-converting enzyme in human atria during atrial fibrillation.

By A. Goette, T. Staack, Christoph Röcken, M. Arndt, J. Geller, C. Huth, S. Ansorge, Helmut U. Klein, U. Lendeckel. Journal of the American College of Cardiology, 2000

598 citations recorded by the source corpus.

Subfields: Cardiology and Cardiovascular Medicine, Hematology

View Paper: https://www.semanticscholar.org/paper/aac0818888eb44de1d2bd52eeca480b114053ef1

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cardiology and Cardiovascular Medicine

1. Stanley Nattel
2. Gerhard Hindricks
3. Ulrich Schotten
4. A. Goette
5. Paulus Kirchhof
6. Gregory Y. H. Lip

Citations in the corpus

• New ideas about atrial fibrillation 50 years on (2002, background): “Individuals affected with AF are known to have upregulated levels of atrial extracellular signal-related kinase (ERK) and angiotensin-converting enzyme (ACE”
• Enalapril Decreases the Incidence of Atrial Fibrillation in Patients With Left Ventricular Dysfunction Insight From the Studies Of Left Ventricular Dysfunction (SOLVD) Trials (2003, unknown): “Detection:12-lead ECG 44 (97.8) 10 (100) Detection: Holter monitoring 1 (2.2) 0 (0) Paroxysmal 43 (95.6) 8 (80) Persistent 2 (4.4) 2 ( 20 ) Requiring hospitalization 23 (51.1) 8 (80) Requiring electrical cardioversion 5 (11.1) 1 (10) Values are number (percent).”
• Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC). (2010, background): “There is good experimental evidence of antifibrillatory and antifibrotic actions of ACEIs and ARBs in various AF models.(144,145)”
• A multicenter risk index for atrial fibrillation after cardiac surgery. (2004, background): “Withdrawal of ACE inhibitor therapy may, in turn, up-regulate receptor subtypes and promote the structural and electrical remodeling of the atria.(23) Cardiopulmonary bypass is associated with an ischemia-reperfusion injury, inducing a complex inflammatory response.”
• 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS. (2016, unknown): “Inhibition of the renin–angiotensin–aldosterone system can prevent structural remodelling and recurrent AF.(236,244) A recent analysis of the Danish healthcare database with long-term monitoring of the effect of different antihypertensive agents on the occurrence of overt AF suggests a beneficial ef”
• ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation-executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committ (2006, unknown): “Angiotensin II is upregulated in response to stretch (32), and atrial tissue from patients with persistent AF demonstrates increased expression of angiotensin-converting enzyme (ACE) (33).”
• ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation--executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Commit (2006, unknown): “Angiotensin II is upregulated in response to stretch,(32) and atrial tissue from patients with persistent AF demonstrates increased expression of angiotensin-converting enzyme (ACE).(33) Angiotensin inhibition may prevent AF by reducing fibrosis.”