Atherogenesis in perspective: Hypercholesterolemia and inflammation as partners in crime

By D. Steinberg. Nature Medicine, 2002

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Therapeutic Potential of Moringa oleifera Leaves in Chronic Hyperglycemia and Dyslipidemia: A Review (2012, background): “These complications could lead to coronary artery disease (CAD), myocardial infarction, thromboembolic stroke, and peripheral artery disease (Steinberg, 2002; Libby et al., 2011).”
Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives (2011, background): “At sites of lesion predilection, disturbed blood flow coupled with hyperlipidemia results in EC activation, which leads to fatty streak formation (541).”
Detection and interpretation of shared genetic influences on 42 human traits (2016, positive): “For example, individuals with congenital hypercholesterolemia also have elevated risk of heart disease 5 ; this is now interpreted as evidence that changes in lipid levels causally influence heart disease risk 6 .”