Plants as a source of anti-cancer agents.
By G. Cragg, D. Newman. Journal of Ethnopharmacology, 2005
2,032 citations recorded by the source corpus.
Plant-derived compounds have been an important source of several clinically useful anti-cancer agents. These include vinblastine, vincristine, the camptothecin derivatives, topotecan and irinotecan, etoposide, derived from epipodophyllotoxin, and paclitaxel (taxol A number of promising new agents are in clinical development based on selective activity against cancer-related molecular targets, including flavopiridol and combretastin A4 phosphate, while some agents which failed in earlier clinical studies are stimulating renewed interest.
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Citations in the corpus
- Natural products for cancer chemotherapy (2011, background): “Of the 126 small molecules among them, 67% are natural in origin (Cragg and Newman, 2005).”
- Flavonoids and Other Phenolic Compounds from Medicinal Plants for Pharmaceutical and Medical Aspects: An Overview (2018, background): “1/record/kew-2607025)] is an example of anticancer drugs originated from phytochemical compound for lymphomas and leukemia treatments [33,34].”