Learning the ABCs of Bt: ABC transporters and insect resistance to Bacillus thuringiensis provide clues to a crucial step in toxin mode of action

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Diversity of bacillus thuringiensis crystal toxins and mechanism of action (2014, background): “proteins in animals (Heckel, 2012).”
An overview of the main pathways of metabolic resistance in insects (2016, background): “…species a mutant allele has been discovered which confers resistance to the pore-forming Cry1Ac toxin from Bacillus thuringiensis (Bt) by a mechanism that is not related to toxin extrusion, but because it causes the loss of Cry1Ac binding to membrane vesicles (Gahan et al., 2010; Heckel, 2012).”